4-Fluoromethamphetamine (4-FMA) is a lesser-known novel stimulant-entactogen substance of the amphetamine class. 4-Fluoromethamphetamine (4-FMA) is chemically related to 4-FA and methamphetamine.

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Description of 4-Fluoromethamphetamine (4-FMA):

4-Fluoromethamphetamine (4-FMA) is a lesser-known novel stimulant-entactogen substance of the amphetamine class. 4-Fluoromethamphetamine (4-FMA) is chemically related to 4-FA and methamphetamine. Little is known about its pharmacology, but it likely produces its effects by increasing levels of dopamine, norepinephrine, and serotonin in the brain.

It has been sold online as a research chemical alongside 2-fluoroamphetamine (2-FA), 3-fluoroamphetamine (3-FA) and 4-fluoroamphetamine (4-FA).

User reports describe the effects of 4-Fluoromethamphetamine (4-FMA) as having characteristics of both traditional stimulants like amphetamine and entactogens like MDMA. Its effects have been described as subjectively lying between 4-FA and 2-FMA. It has been reported to be more likely to produce side effects like headaches and cardiovascular effects than similar substances.

Very little is known about the pharmacological properties, metabolism, and toxicity of 4-Fluoromethamphetamine (4-FMA). 4-Fluoromethamphetamine (4-FMA) use may produce dependence and abuse as well as damage to the brain and other organs. It is highly advised to use harm reduction practices if using 4-Fluoromethamphetamine (4-FMA).

How 4-Fluoromethamphetamine (4-FMA) works:
Similar to its structural analog 4-FA, 4-Fluoromethamphetamine is thought to act as a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine, producing stimulating amphetamine-like effects at lower doses and more euphoric, entactogen effects similar to MDA at dosages above 125mg. Researchers have found some evidence that indicates some similarities between the “Serotonin Release” of 4-Fluoromethamphetamine (4-FMA) and other popular empathogens such as: MDA, 4-Methylmethcathinone, and 4-fluoroamphetamine.

The mechanism of action of 4-Fluoromethamphetamine (4-FMA) effectively boosts the levels of the norepinephrine, dopamine, and serotonin neurotransmitters in higher doses in the brain by binding to and partially blocking the transporter proteins that normally clear these monoamines from the synaptic cleft. This allows dopamine, norepinephrine, and serotonin to accumulate within various regions of the brain, including its reward pathways, resulting in stimulating, euphoric and entactogenic effects.

Effects of 4-Fluoromethamphetamine (4-FMA)
It reduces the metabolism of methamphetamine, which has the effect of increasing its potency, duration and systemic toxicity while also reducing its cellular toxicity.

As long as you take a common dose, it’s usually free of most negative effects. This means little to no jitteriness, noticeable cardiovascular effects, sweating, or anxiety. With higher doses (e.g. over 50 mg), jitteriness, sweating, jaw tightness, muscle tension, and possibly heart palpitations can develop.

Physical effects of 4-Fluoromethamphetamine (4-FMA)

*Stimulation- The stimulation which 4-Fluoromethamphetamine presents can be described as being a mix between a typical entactogen stimulation and the stimulation style of Methamphetamine.
*Tactile enhancement – This component, relative to other fluorinated amphetamines like 2-FA or 3-FA, has been reported to be a distinct aspect of the experience.
*Physical euphoria – This effect is extremely intense when compared to its physical stimulation.
*Bodily control enhancement
*Pupil dilation
*Appetite suppression
*Orgasm suppression
*Increased perspiration
*Increased bodily temperature
*Increased heart rate
*Temporary erectile dysfunction
*Teeth grinding
*Vibrating vision
*Restless leg syndrome
*Muscle contractions
*Abnormal heartbeat

After effects Aftereffects of 4-Fluoromethamphetamine

The effects which occur during the offset of a stimulant experience generally feel negative and uncomfortable in comparison to the effects which occurred during its peak. This is often referred to as a “comedown” and occurs because of neurotransmitter depletion. Its effects commonly include:
Cognitive fatigue
Motivation suppression
Thought deceleration
Suicidal ideation

***2-Fluoromethamphetamine (2-FMA) is also available for purchase.

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